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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 545149Generated: October 28, 2026

4-(2-(4-Bromophenoxy)ethyl)morpholine → 4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholine

https://huagongshe.com/reaction/545149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-(4-Bromophenoxy)ethyl)morpholineHCID 2053815—
Reactant(6-Fluoropyridin-3-yl)boronic acidHCID 2783397—
ReactantTirbanibulinHCID 23635314—
Product4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholineHCID 44185420—

Reaction Steps

In another aspect, the invention relates to a process for preparing 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide comprising the step of coupling 4-(2-(4-bromophenoxy)ethyl)morpholine with 6-fluoropyridin-3-yl-3-boronic acid to yield 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935697B2
Source datasetuspto-grants-2011_05
ORD IDord-0b7fddf44d424b73be75939ea278a80a
Source noteuspto-grants-2011_05