HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 8-Cyclopropyl-4-(2-hydroxyethoxy)-1,7-naphthyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 1-Acetoxy-2-bromoethane | HCID 13564 | — |
| Reactant | HCID 178524589 | HCID 178524589 | — |
| Product | 8-Cyclopropyl-4-(2-hydroxyethoxy)-1,7-naphthyridine-2-carboxylic acid | HCID 67170213 | — |
Reaction Steps
The intended compound was produced according to the procedures described in reference examples 35 and 36 but using 8-cyclopropyl-4-hydroxy-[1,7]naphthyridine-2-carboxylic acid and acetic acid 2-bromoethyl ester in place of 1-Cyclopropyl-5-hydroxy-isoquinoline-7-carboxylic acid methyl ester and iodomethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935712B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-5a5bff9ea0f648389bf803ad91d9ef17 |
| Source note | uspto-grants-2011_05 |