Fumaric Acid → HCID 67170365, compound

HRID 545301Notes

Reaction equation

HRID 545301 reaction equation
[N:1]1([C@H:7]2[CH2:11][CH2:10][N:9]([C:12]([C:14]3[CH:19]=[CH:18][C:17]([N:20]4[C:24]5[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=5[N:22]=[CH:21]4)=[CH:16][CH:15]=3)=O)[CH2:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:29]([OH:36])(=[O:35])/[CH:30]=[CH:31]/[C:32]([OH:34])=[O:33]>>[C:29]([OH:36])(=[O:35])/[CH:30]=[CH:31]/[C:32]([OH:34])=[O:33].[N:1]1([C@H:7]2[CH2:11][CH2:10][N:9]([CH2:12][C:14]3[CH:15]=[CH:16][C:17]([N:20]4[C:24]5[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=5[N:22]=[CH:21]4)=[CH:18][CH:19]=3)[CH2:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 444972Fumaric AcidHCID 24896764HCID 24896764, compound

Product 1

HCID 67170365HCID 67170365, compound

Procedure

Using essentially the same procedure described in Example 14 and employing 1-(4-{[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]carbonyl}phenyl)-1H-benzimidazole as starting material and fumaric acid, the title compound was obtained and identified by NMR and mass spectral analyses. MS [361.2 m/e (M+H)].

Sources & evidence

ORD record
ord-1dee098a83f146828203c0d8f3c12918
Source dataset
uspto-grants-2011_05
Patent number
US07935719B2

Reaction notes

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