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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 54533Generated: October 28, 2026

Benzenemethanol, 3-(2-quinolinylmethoxy)- → 2-(3-Chloromethylphenoxy)methylquinoline

https://huagongshe.com/reaction/54533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenemethanol, 3-(2-quinolinylmethoxy)-HCID 14650410—
Reactant4-(7-Chloroquinolin-2-ylmethoxy)benzyl alcoholHCID 53740133—
Product2-(3-Chloromethylphenoxy)methylquinolineHCID 1450170672%

Reaction Steps

The procedure from Example 6, part B was used except 3-(quinolin-2-ylmethoxy)benzyl alcohol was substituted for 4-(7-chloroquinolin-2-ylmethoxy)benzyl alcohol. The intermediate was obtained in 72% yield: mp 39°-43° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05622969
Source datasetuspto-grants-1997_04
ORD IDord-3d167a1e51a64edb81a0a6863312ee2c
Source noteuspto-grants-1997_04