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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 54534Generated: October 29, 2026

4-(Quinolin-2-ylmethoxy)benzyl alcohol → 2-(4-Chloromethylphenoxy)methylquinoline

https://huagongshe.com/reaction/54534

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Quinolin-2-ylmethoxy)benzyl alcoholHCID 28775506—
Reactant4-(7-Chloroquinolin-2-ylmethoxy)benzyl alcoholHCID 53740133—
Product2-(4-Chloromethylphenoxy)methylquinolineHCID 1477416347%

Reaction Steps

The procedure from Example 6, part B was used except 4-(quinolin-2-ylmethoxy)benzyl alcohol was substituted for 4-(7-chloroquinolin-2-ylmethoxy)benzyl alcohol. The intermediate was obtained in 47% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05622969
Source datasetuspto-grants-1997_04
ORD IDord-43a1e498f73c49d4ad930a4bcb5a4155
Source noteuspto-grants-1997_04