HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-1H-1,2,4-triazole-3-carboxylic acid → 3-(1-Benzyl-1H-[1,2,4]triazol-3-yl)-2-[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-3-oxo-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-1H-1,2,4-triazole-3-carboxylic acid | HCID 15707919 | — |
| Reactant | [Cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester | HCID 67133328 | — |
| Product | 3-(1-Benzyl-1H-[1,2,4]triazol-3-yl)-2-[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-3-oxo-propionic acid ethyl ester | HCID 67133090 | — |
Reaction Steps
The title compound, a colorless oil (1.1 g, 50%), was prepared in analogy to intermediate 8A by reaction of [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester (intermediate 7B) with 1-benzyl-1H-[1,2,4]triazole-3-carboxylic acid. MS: 517.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935707B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-305c1edcf43f4e83a32f29efd2377724 |
| Source note | uspto-grants-2011_05 |