1-Benzyl-1H-1,2,3-triazole-4-carboxylic acid → HCID 67133208, compound

HRID 545354Notes

Reaction equation

HRID 545354 reaction equation
[CH2:1]([O:3][C:4](=[O:23])[CH2:5][N:6]([CH:20]1[CH2:22][CH2:21]1)[C:7](=[O:19])[C:8]1[CH:13]=[CH:12][C:11]([O:14][C:15]([F:18])([F:17])[F:16])=[CH:10][CH:9]=1)[CH3:2].[CH2:24]([N:31]1[CH:35]=[C:34]([C:36](O)=[O:37])[N:33]=[N:32]1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:1]([O:3][C:4](=[O:23])[CH:5]([N:6]([CH:20]1[CH2:22][CH2:21]1)[C:7](=[O:19])[C:8]1[CH:9]=[CH:10][C:11]([O:14][C:15]([F:16])([F:17])[F:18])=[CH:12][CH:13]=1)[C:36]([C:34]1[N:33]=[N:32][N:31]([CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:35]=1)=[O:37])[CH3:2]

Participants

3

Reactant 2

HCID 162277901-Benzyl-1H-1,2,3-triazole-4-carboxylic acidHCID 67133328[Cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester2×

Product 1

HCID 67133208HCID 67133208, compound

Procedure

The title compound, a colorless oil (0.6 g, 27%), was prepared in analogy to intermediate 8A by reaction of [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester (intermediate 7B) with 1-benzyl-1H-[1,2,3]triazole-4-carboxylic acid. MS: 517.1 (MH+).

Sources & evidence

ORD record
ord-0397f7b870914b6e9bc338b1ab633bbf
Source dataset
uspto-grants-2011_05
Patent number
US07935707B2

Reaction notes

Loading…