HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Pyridin-4-yl)boronic acid → [2-(3-Hexyl-phenyl)-3-methyl-5-pyridin-4-yl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Pyridin-4-yl)boronic acid | HCID 2734379 | — |
| Reactant | [2-(3-Hexyl-phenyl)-5-iodo-3-methyl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone | HCID 57541122 | — |
| Product | [2-(3-Hexyl-phenyl)-3-methyl-5-pyridin-4-yl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone | HCID 57541102 | — |
Reaction Steps
In analogy to the procedure described for example 7, [2-(3-hexyl-phenyl)-5-iodo-3-methyl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 2) was reacted with pyridin-4-yl-boronic acid to give the title compound as light yellow oil. MS: 500.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935707B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-5cd62763c89d4332927dd3d55360d29f |
| Source note | uspto-grants-2011_05 |