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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 545384Generated: October 28, 2026

Trimethylsilylacetylene → HCID 57541124, compound

https://huagongshe.com/reaction/545384

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantHCID 25152481HCID 25152481—
ProductHCID 57541124HCID 57541124—

Reaction Steps

In analogy to the procedure described for example 12, [5-iodo-3-methyl-2-(3-trifluoromethoxy-phenyl)-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 19) was reacted with trimethylsilylacetylene to give the title compound as dark brown gum. MS: 519.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935707B2
Source datasetuspto-grants-2011_05
ORD IDord-30182e339fce4102890b442bcf91d766
Source noteuspto-grants-2011_05