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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 545393Generated: October 29, 2026

[2-(3-Hexyl-phenyl)-5-(3-hydroxy-prop-1-ynyl)-3-methyl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone → HCID 57541077, compound

https://huagongshe.com/reaction/545393

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[2-(3-Hexyl-phenyl)-5-(3-hydroxy-prop-1-ynyl)-3-methyl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanoneHCID 57541113—
CatalystPlatinum oxide (PtO)HCID 82844—
ProductHCID 57541077HCID 57541077—

Reaction Steps

In analogy to the procedure described for example 14, [2-(3-hexyl-phenyl)-5-(3-hydroxy-prop-1-ynyl)-3-methyl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 31) was hydrogenated using platinum oxide as catalyst to give the title compound as yellow oil. MS: 481.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935707B2
Source datasetuspto-grants-2011_05
ORD IDord-736fb6932941417a89e80d9dd9f94346
Source noteuspto-grants-2011_05