HCID 57541151, compound → HCID 57541171, compound

HRID 545394Notes

Reaction equation

HRID 545394 reaction equation
[CH2:1]([C:7]1[CH:8]=[C:9]([C:13]2[N:17]([CH3:18])[C:16]([C:19]([N:21]3[CH2:26][CH2:25][CH:24]([N:27]4[CH2:31][CH2:30][CH2:29][CH2:28]4)[CH2:23][CH2:22]3)=[O:20])=[C:15]([C:32]#[C:33][CH2:34][O:35][CH3:36])[N:14]=2)[CH:10]=[CH:11][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]>[Pt]=O>[CH2:1]([C:7]1[CH:8]=[C:9]([C:13]2[N:17]([CH3:18])[C:16]([C:19]([N:21]3[CH2:26][CH2:25][CH:24]([N:27]4[CH2:31][CH2:30][CH2:29][CH2:28]4)[CH2:23][CH2:22]3)=[O:20])=[C:15]([CH2:32][CH2:33][CH2:34][O:35][CH3:36])[N:14]=2)[CH:10]=[CH:11][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

3

Reactant 1

HCID 57541151HCID 57541151, compound

Product 1

HCID 57541171HCID 57541171, compound

Reagents, catalysts & solvents 1

HCID 82844Platinum oxide (PtO)Catalyst

Procedure

In analogy to the procedure described for example 14, [2-(3-hexyl-phenyl)-5-(3-methoxy-prop-1-ynyl)-3-methyl-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 32) was hydrogenated using platinum oxide as catalyst to give the title compound as light yellow oil. MS: 495.4 (MH+).

Sources & evidence

ORD record
ord-c34384215fc74eff8a22d494e2817435
Source dataset
uspto-grants-2011_05
Patent number
US07935707B2

Reaction notes

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