HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 25152484, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | HCID 25152481 | HCID 25152481 | — |
| Catalyst | Zinc cyanide (Zn(CN)2) | HCID 11186 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Product | HCID 25152484 | HCID 25152484 | — |
Reaction Steps
In analogy to the procedure described for example 18, [5-iodo-3-methyl-2-(3-trifluoromethoxy-phenyl)-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 19) was reacted with zinc cyanide and tetrakis-(triphenylphosphine)-palladium in DMF to give the title compound as colorless foam. MS: 448.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935707B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-8547fa41715347d8af70347e03d57ede |
| Source note | uspto-grants-2011_05 |