3-Pyridinylboronic acid → [2-(3-Hexyl-phenyl)-3-methyl-5-pyridin-3-yl-3H-imidazol-4-yl]-[4-((R)-2-hydroxymethyl-pyrrolidin-1-yl)-piperidin-1-yl]-methanone

Beteiligte Stoffe

Reaktionsschritte

In analogy to the procedure described for example 7, [2-(3-hexyl-phenyl)-5-iodo-3-methyl-3H-imidazol-4-yl]-[4-((R)-2-hydroxymethyl-pyrrolidin-1-yl)-piperidin-1-yl]-methanone (example 45) was reacted with pyridin-3-yl-boronic acid to give the title compound as light brown oil. MS: 530.3 (MH+).

Herkunft & Nachweise