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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 545446Generated: October 28, 2026

[5-iodo-3-methyl-2-(4-trifluoromethyl-phenyl)-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone → HCID 178479935, compound

https://huagongshe.com/reaction/545446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[5-iodo-3-methyl-2-(4-trifluoromethyl-phenyl)-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanoneHCID 57541088—
ReactantHCID 178431084HCID 178431084—
ProductHCID 178479935HCID 178479935—

Reaction Steps

In analogy to the procedure described for example 7, [5-iodo-3-methyl-2-(4-trifluoromethyl-phenyl)-3H-imidazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 104) was reacted with 6-hydroxy-pyridin-3-yl-boronic acid pinacol ester to give the title compound as off-white solid. MS: 500.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935707B2
Source datasetuspto-grants-2011_05
ORD IDord-1bb9bd1e364b41249697a67abf2ab965
Source noteuspto-grants-2011_05