3-Fluorobenzyl bromide → HCID 67197367, compound

Participants

Reaction Steps

Alkylate (R)-N-(6-Bromo-2,3,4,9-tetrahydro-1H-carbazol-3-yl)isobutyramide with 1-bromomethyl-3-fluorobenzene using procedures essentially as described in Example 1 to give the title compound. MS (ES): m/z 443 (M+1), 445 (M+1+2); m.p.=204-207° C. (Alkylate the S isomer in a similar fashion to obtain (S)-N-(9-Benzyl-6-bromo-2,3,4,9-tetrahydro-1H-carbazol-3-yl)isobutyramide.)

Provenance & Evidence