2-Amino-5-bromopyridine → 5-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine

HRID 545534Notes

Reaction equation

HRID 545534 reaction equation
[Br:1][C:2]1S[C:5]([N:7]2[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[CH3:13])=[N:4][CH:3]=1.N[C:15]1[CH:20]=CC(Br)=CN=1>>[Br:1][C:2]1[CH:15]=[CH:20][C:5]([N:7]2[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[CH3:13])=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 706222-Amino-5-bromopyridineHCID 534183755-Bromo-2-(2,5-dimethylpyrrol-1-yl)thiazole

Product 1

HCID 120436225-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine

Procedure

Prepare using procedures essentially as described for 5-bromo-2-(2,5-dimethylpyrrol-1-yl)thiazole (Preparation 25) starting with 2-amino-5-bromopyridine. MS (ES): m/z 252 (M+1).

Workup

  1. customPrepare

Sources & evidence

ORD record
ord-058285a44a28495790fa80a489577336
Source dataset
uspto-grants-2011_05
Patent number
US07935722B2

Reaction notes

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