HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenylhydrazine Hydrochloride → Cyclopropanecarboxylic acid(6-cyano-2,3,4,9-tetrahydro-1h-carbazol-3-yl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenylhydrazine Hydrochloride | HCID 16212962 | — |
| Reactant | N-(4-oxocyclohexyl)cyclopropanecarboxamide | HCID 43652864 | — |
| Product | Cyclopropanecarboxylic acid(6-cyano-2,3,4,9-tetrahydro-1h-carbazol-3-yl)amide | HCID 59161240 | — |
Reaction Steps
Prepare the title compound from cyclopropanecarboxylic acid(4-oxocyclohexyl)amide (51.3 g, 283 mmol) and 4-cyanophenylhydrazine hydrochloride (48.0 g, 283 mmol) by essentially following procedures as described in Preparation 3 to obtain 57.0 g (72%) of a pale yellow solid. mp: 231-233° C.; MS (ES): m/z 280 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935722B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-c726b969fece48519170a5cd476219fd |
| Source note | uspto-grants-2011_05 |