HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one → 3-(5-bromo-2-hydroxyphenyl)-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one | HCID 12004333 | — |
| Reactant | 4-bromo-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-one | HCID 12004400 | — |
| Product | 3-(5-bromo-2-hydroxyphenyl)-1,3-dihydro-2H-indol-2-one | HCID 58872457 | — |
Reaction Steps
Following the procedure as described in PREPARATION 1D, and making non-critical variations to replace 4-bromo-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-one with 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one, the title compound was obtained (98%) as a white powder: MS (ES+) m/z 306.2 (M+1), 304.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935721B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-67b00779f937471aafb3f520c64ef2db |
| Source note | uspto-grants-2011_05 |