Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 545787Generated: October 30, 2026

3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one → 3-(5-bromo-2-hydroxyphenyl)-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/545787

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-oneHCID 12004333—
Reactant4-bromo-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-oneHCID 12004400—
Product3-(5-bromo-2-hydroxyphenyl)-1,3-dihydro-2H-indol-2-oneHCID 58872457—

Reaction Steps

Following the procedure as described in PREPARATION 1D, and making non-critical variations to replace 4-bromo-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-one with 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one, the title compound was obtained (98%) as a white powder: MS (ES+) m/z 306.2 (M+1), 304.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935721B2
Source datasetuspto-grants-2011_05
ORD IDord-67b00779f937471aafb3f520c64ef2db
Source noteuspto-grants-2011_05