HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-5-(trifluoromethyl)furan → HCID 59263350, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-5-(trifluoromethyl)furan | HCID 2794605 | — |
| Reactant | Cyclopropane, 1-(bromomethyl)-2-methyl- | HCID 21891724 | — |
| Reactant | spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one | HCID 53375495 | — |
| Reactant | 5,5-dimethyl-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-2'(1H)-one | HCID 59263470 | — |
| Product | HCID 59263350 | HCID 59263350 | — |
Reaction Steps
Following the procedure described in EXAMPLE 10.21, and making non-critical variations using spiro[furo[2,3-f][1,3]benzodioxole-7,3′-indol]-2′(1′H)-one to replace 5,5-dimethyl-5,6-dihydrospiro[benzo[1,2-b:5,4-b′]difuran-3,3′-indol]-2′(1′H)-one, and 1-(bromomethyl)-2-methylcyclopropane to replace 2-(bromomethyl)-5-(trifluoromethyl)furan, the title compound was obtained (37%) as a white solid: MS (ES+) m/z 350.3 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935721B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-ef11bd0534fa4e1f8bd8738ae69aa842 |
| Source note | uspto-grants-2011_05 |