反应详情

Dissolve 2-propyl-3-t-butyl-5-isopropylbenzoquinone (10 mmol), 1,1,3,3-tetramethyldisiloxane (1.79 mL, 10 mmol) and iodine (0.05 g) in methylene chloride (30 mL). Stir at reflux for 30 minutes and extract with 1N sodium hydroxide (30 mL). Acidify the aqueous phase with concentrated hydrochloric acid and extract into ethyl acetate (4×10 mL), dry (Na2SO4) and evaporate the solvent in vacuo to give 2-propyl-3-t-butyl-4-hydroxy-5-isopropylphenol.

1. temperatureat reflux for 30 minutes
2. extractionextract with 1N sodium hydroxide (30 mL)
3. extractionextract into ethyl acetate (4×10 mL)
4. dry with materialdry (Na2SO4)
5. customevaporate the solvent in vacuo