Triethylamine → HCID 11456665, compound

Participants

Reaction Steps

Dissolve 12.7 g (32 mmol) the compound 10 and 10.2 g (32 mmol) the compound 9 into 60 mL dichloromethane. Then add 6.7 mL (48 mmol) triethylamine followed by a heat flow process for two days. After cooling, wash with 60 mL Sodium hydrogen carbonate aqueous solution, and wash again with 60 mL water, take the organic layer. The organic phase is dried by Na2SO4, condensed and then purified by liquid chromatography (SiO2, ethyl acetate: hexane=1:1) to get light yellow oil product 11 (12.9 g, 59.9%).

Provenance & Evidence