HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilyldiazomethane → 2-Acetamidoacrylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilyldiazomethane | HCID 167693 | — |
| Reactant | (S)-Methyl 2-acetamidopropanoate | HCID 6951030 | — |
| Product | 2-Acetamidoacrylic acid | HCID 79482 | — |
Reaction Steps
(S)-2-Acetylaminopropionic acid methyl ester, conversion>99%, ee>99% (derivatised using TMS-diazomethane and then analysed using the same method developed for the methyl ester).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935841B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-099ac82866b340beb0efcec807ffb5ee |
| Source note | uspto-grants-2011_05 |