6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline → 3,4-Dihydro-6,7-dimethoxy-1-methylisoquinoline

Participants

Reaction Steps

6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline, conversion>99%, ee 82% (GC, sample derivatised by treatment with acetic anhydride pyridine, Chirasil DEX CB, 25 m×0.25 mm, injector/detector 200° C., helium 20 psi, 170° C. for 20 minutes then ramp at 5° C./min to 200° C., hold for 10 minutes, retention times 30.18 minutes and 30.45 minutes).

Provenance & Evidence