HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Dioxide → HCID 11208658, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Dioxide | HCID 280 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | HCID 67199471 | HCID 67199471 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11208658 | HCID 11208658 | — |
Reaction Steps
(R)-2-Acetylamino-3,3-diphenylpropionic acid methyl ester, reaction time 6 h, conversion 100%. [α]D25-101.6 (c=1.02, CHCl3). ee 80.7% (SFC, 2× Chiralpak AD-H columns, 10% methanol, 3000 psi CO2, 35° C., flow rate 3 ml/minute, retention times R 5.2 minutes, S 10.1 minutes). Comparative examples have been disclosed by Boulton (Boulton, L. T., WO 2006127273).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935841B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-f3fa9e88badb4a92bb78941d66afff26 |
| Source note | uspto-grants-2011_05 |