(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexane-1-carbaldehyde → 1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)-4-phenylbutan-1-one

HRID 546372Notes

Reaction equation

HRID 546372 reaction equation
[CH:1]([C@@H:4]1[CH2:9][CH2:8][C@@H:7]([CH3:10])[CH2:6][C@H:5]1[CH:11]=[O:12])([CH3:3])[CH3:2].[C:13]1([CH2:19][CH2:20][CH2:21][Mg]Br)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH:1]([C@@H:4]1[CH2:9][CH2:8][C@@H:7]([CH3:10])[CH2:6][C@H:5]1[C:11](=[O:12])[CH2:21][CH2:20][CH2:19][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 11252239(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexane-1-carbaldehydeHCID 178418471HCID 178418471, compound

Product 1

HCID 671902261-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)-4-phenylbutan-1-one

Procedure

The title compound was prepared following the general procedure of Example 1 starting from (1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbaldehyde and (3-phenylpropyl)magnesium bromide.

Sources & evidence

ORD record
ord-59afda6c5bd74164bd82b40346044eac
Source dataset
uspto-grants-2011_05
Patent number
US07935848B2

Reaction notes

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