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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 546404Generated: October 30, 2026

Water → HCID 23712812, compound

https://huagongshe.com/reaction/546404

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium HydroxideHCID 3939—
ReactantHCID 17842376HCID 17842376—
SolventTetrahydrofuranHCID 8028—
ProductHCID 23712812HCID 23712812107.6%

Reaction Steps

Water (6.0 ml) and lithium hydroxide (99.7 mg) were added to a solution of 2-methoxycarbonyl-5-methyl-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine (800 mg) in tetrahydrofuran (24 ml) at room temperature, and the mixture was stirred for 10 minutes. The reaction mixture was concentrated under reduced pressure to obtain the title compound (825 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935824B2
Source datasetuspto-grants-2011_05
ORD IDord-2f802f0b52c14f7489a4d93dc4d06641
Source noteuspto-grants-2011_05