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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 546671Generated: November 1, 2026

Hydrochloric Acid → 5-Chloro-2-(3,4,5-trifluorophenyl)pentanoic acid hydrazide hydrochloride

https://huagongshe.com/reaction/546671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-butyl N'-[5-chloro-2-(3,4,5-trifluorophenyl)pentanoyl]hydrazinecarboxylateHCID 66839143—
SolventEthyl AcetateHCID 8857—
Product5-Chloro-2-(3,4,5-trifluorophenyl)pentanoic acid hydrazide hydrochlorideHCID 66839231200.1%

Reaction Steps

A solution of 4 N hydrochloric acid in ethyl acetate (2 mL) was added to a solution of tert-butyl N′-[5-chloro-2-(3,4,5-trifluorophenyl)pentanoyl]hydrazinecarboxylate (300 mg) in ethyl acetate (2 mL), and the reaction solution was stirred at room temperature for one hour. The reaction solution was concentrated under reduced pressure to obtain 250 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935815B2
Source datasetuspto-grants-2011_05
ORD IDord-1f08c4ffc60a4ea795d3c9234a77bcd7
Source noteuspto-grants-2011_05