HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 7-Methoxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 7-Methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline | HCID 14719548 | — |
| Product | 7-Methoxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide | HCID 19959703 | — |
Reaction Steps
640 mg of 7-methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline was dissolved in 13 ml of 48% aqueous hydrogen bromide, and the mixture was heated under reflux under an argon gas stream for 3 hours. The reaction solution was cooled, and crystals which separated out were collected, affording 580 mg of 7-methoxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623074 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-f5fe4cfcbae04d3f976fa5d7725eebce |
| Source note | uspto-grants-1997_04 |