Ethyl Acetate → HCID 66839506, compound

Participants

Reaction Steps

TBAF (2.7 mL; 1 M solution in THF) was added to a solution of tert-butyl N′-[5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoyl]hydrazinecarboxylate (1.04 g) in THF (20 mL). The reaction solution was stirred at room temperature for 1 hours. Then, ethyl acetate and a saturated ammonium chloride solution were added to the reaction solution, and the organic layer was separated. The resulting organic layer was washed with brine, dried over anhydrous magnesium sulfate and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (elution solvent: heptane-ethyl acetate system) to obtain 525 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence