反应详情

2-[2-(Toluene-4-sulfinyl)ethyl]-8-(2-trifluoromethylphenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridine (8.87 g) was dissolved in toluene (300 ml), and the reaction solution was heated under reflux for three days. After leaving to cool, the reaction solution was concentrated under reduced pressure. The residue was purified by silica gel column chromatography to obtain the title compound (4.27 g). The property values of the compound are as follows.

1. temperaturethe reaction solution was heated
2. temperatureunder reflux for three days
3. customAfter leaving
4. temperatureto cool
5. concentrationthe reaction solution was concentrated under reduced pressure
6. customThe residue was purified by silica gel column chromatography