HCID 57708933, compound → HCID 57709030, compound

Participants

Reaction Steps

10% palladium carbon (11.3 mg) was added to a solution of 2-(4-{1-ethyl-1-[3-methyl-4-(1-trimethylsilanyloxy-cyclohexylethynyl)-phenyl]-propyl}-2-methyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (Example 35-(4); 49.7 mg, 0.0867 mmol) in ethyl acetate (0.5 mL), and the mixture was stirred under hydrogen charging for three hours. The reaction mixture was filtered and concentrated to give the title compound (43.3 mg, 86%).

Provenance & Evidence