反应详情

A solution of 3,4,4-trifluoro-3-butenoyl chloride (2.8 g, 0.0176 mole) and benzyl alcohol (0.9 g, 0.0083 mole) in 20 mL dichloromethane is heated at reflux for 40 h. The solution is cooled to room temperature, diluted with dichloromethane (15 mL), washed successively with 5% sodium bicarbonate, water and brine, and dried. Evaporation of the solvent gave 1.75 g of analytically pure product as a pale yellow oil, a 92% yield.

1. temperatureat reflux for 40 h
2. washwashed successively with 5% sodium bicarbonate, water and brine
3. customdried
4. customEvaporation of the solvent
5. customgave 1.75 g of analytically pure product as a pale yellow oil