HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 54735Generated: October 25, 2026
1-Octanethiol → 3,4,4-trifluoro-3-butenethioic acid, S-octyl ester
https://huagongshe.com/reaction/54735
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Octanethiol | HCID 8144 | — |
| Reactant | 3,4,4-Trifluoro-3-butenoyl chloride | HCID 10920789 | — |
| Product | 3,4,4-trifluoro-3-butenethioic acid, S-octyl ester | HCID 15239192 | 91.3% |
Reaction Steps
A mixture of 3,4,4-trifluoro-3-butenoyl chloride (1.7 g, 0.0107 mole) and 1-octanethiol (0.72 g, 0.0049 mole) is heated at 70° C. for 12 h. The crude product is purified by passing through a short column of silica gel to give 1.2 g of the desired product as a pale yellow oil, a 91% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05623084 |
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| Source dataset | uspto-grants-1997_04 |
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| ORD ID | ord-eb0dbc9d20ca481b847892b364cfb881 |
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| Source note | uspto-grants-1997_04 |
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