HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → N-[(3,4,4-trifluoro-3-butenyl)amino]oxoacetic acid, hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Oxo[(3,4,4-trifluoro-3-butenyl)amino]oxoacetic acid, methyl ester | HCID 86748464 | — |
| Product | N-[(3,4,4-trifluoro-3-butenyl)amino]oxoacetic acid, hydrazide | HCID 86748463 | 60% |
Reaction Steps
A solution of Compound 142 (4.22 g, 0.02 mole) in absolute ethanol (50 mL) is treated with hydrazine monohydrate (1.6 g, 0.032 mole) with stirring. The precipitate is filtered, washed with ethanol and dried to give 2.54 g of the title compound as a white solid, a 60% yield. m.p. 145°-200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623084 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-ed9ce179bce04f43bee0a0371ac6dae1 |
| Source note | uspto-grants-1997_04 |