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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 547426Generated: October 31, 2026

Tirbanibulin → 2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile

https://huagongshe.com/reaction/547426

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTirbanibulinHCID 23635314—
Reactant4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholineHCID 44185420—
SolventAcetonitrileHCID 6342—
Product2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrileHCID 44185421—

Reaction Steps

In another aspect, the invention relates to a process for preparing 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide comprising the step of reacting 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine with acetonitrile to yield 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07939529B2
Source datasetuspto-grants-2011_05
ORD IDord-080b361cae9e4cf29e40b8f1ec730cc7
Source noteuspto-grants-2011_05