HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 547442Generated: October 31, 2026
4-Methylpyrimidine → Ethenamine, N,N-dimethyl-2-(4-pyrimidinyl)- (9CI)
https://huagongshe.com/reaction/547442
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylpyrimidine | HCID 18922 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethenamine, N,N-dimethyl-2-(4-pyrimidinyl)- (9CI) | HCID 6433770 | 95.1% |
Reaction Steps
A mixture of 10 g of 4-methylpyrimidine, 38 g of N,N-dimethylformamide dimethylacetal (DMFDMA) and 46.6 g of DMF was stirred in a sealed tube at 140° C. for 24 hours. The reaction solution was cooled and the solvent was distilled off under reduced pressure to provide 15.08 g (yield: 95%) of the title compound as brown crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07939536B2 |
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| Source dataset | uspto-grants-2011_05 |
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| ORD ID | ord-9c17e25ad79b4c688b20df8d1503cead |
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| Source note | uspto-grants-2011_05 |
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