HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiopheneboronic acid → (1-Methyl-cyclohexyl)-(2-thiophen-2-yl-5H-pyrrolo[2,3-b]pyrazin-7-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiopheneboronic acid | HCID 2733960 | — |
| Reactant | (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanone | HCID 44199730 | — |
| Product | (1-Methyl-cyclohexyl)-(2-thiophen-2-yl-5H-pyrrolo[2,3-b]pyrazin-7-yl)-methanone | HCID 57829688 | — |
Reaction Steps
(1-Methyl-cyclohexyl)-(2-thiophen-2-yl-5H-pyrrolo[2,3-b]pyrazin-7-yl)-methanone was prepared starting from (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanone and thiophene-2-boronic acid following general procedures described in these Examples. MP 224-225° C., M+H=326.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07939531B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-f6c642ae0f2d4afcbf5f0ebe233b79c8 |
| Source note | uspto-grants-2011_05 |