HCID 57829673, compound → HCID 44193295, compound

HRID 547474Notes

Reaction equation

HRID 547474 reaction equation
C1(S([N:10]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[C:12]([C:19]3[N:20]=[C:21]4[C:27]([C:28]([C:30]5([CH3:36])[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]5)=[O:29])=[CH:26][NH:25][C:22]4=[N:23][CH:24]=3)=[CH:11]2)(=O)=O)C=CC=CC=1>C(Cl)Cl>[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:12]([C:19]2[N:20]=[C:21]3[C:27]([C:28]([C:30]4([CH3:36])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]4)=[O:29])=[CH:26][NH:25][C:22]3=[N:23][CH:24]=2)=[CH:11]1

Participants

3

Reactant 1

HCID 57829673HCID 57829673, compound

Product 1

HCID 44193295HCID 44193295, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

[2-(1H-Indol-3-yl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone was prepared following the same procedure by using [2-(1-benzenesulfonyl-1H-indol-3-yl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone as starting material. The product was obtained in 70% after SiO2 chromatography (DCM/[DCM/MeOH 9.5/1] 10/0 to 0/10).

Sources & evidence

ORD record
ord-f892e3150299420da715c11b06c22dba
Source dataset
uspto-grants-2011_05
Patent number
US07939531B2

Reaction notes

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