HCID 25002289, compound → HCID 66646483, compound

HRID 547496Notes

Reaction equation

HRID 547496 reaction equation
NC1C=C([C:8]2C3C(=CC(OC)=C(OC)C=3)N=[C:10](CN)[N:9]=2)C=CC=1.Cl.[CH3:25][O:26][C:27]1[CH:28]=[C:29]2[C:34](=[CH:35][C:36]=1[O:37][CH3:38])[N:33]=[C:32]([NH:39][CH3:40])[N:31]=[C:30]2[C:41]1[CH:42]=[C:43]([NH:47][C:48](=[O:58])[C:49]2[CH:57]=[CH:56][C:52]([C:53]([OH:55])=O)=[CH:51][CH:50]=2)[CH:44]=[CH:45][CH:46]=1>>[CH3:25][O:26][C:27]1[CH:28]=[C:29]2[C:34](=[CH:35][C:36]=1[O:37][CH3:38])[N:33]=[C:32]([NH:39][CH3:40])[N:31]=[C:30]2[C:41]1[CH:42]=[C:43]([NH:47][C:48](=[O:58])[C:49]2[CH:57]=[CH:56][C:52]([C:53]([N:9]([CH3:10])[CH3:8])=[O:55])=[CH:51][CH:50]=2)[CH:44]=[CH:45][CH:46]=1

Participants

3

Reactant 2

HCID 25002289HCID 25002289, compoundHCID 25196907[4-(3-Aminophenyl)-6,7-dimethoxyquinazolin-2-yl]methylamine

Product 1

HCID 66646483HCID 66646483, compound

Procedure

The following compounds of Examples 4 to 10 were synthesized by methods similar to Example 3, using the compound of Example 2 as a starting substance, and also using the corresponding alcohol or amine.

Sources & evidence

ORD record
ord-234c1df7aa754a5d8b0bf697f5c66522
Source dataset
uspto-grants-2011_05
Patent number
US07939540B2

Reaction notes

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