p-Toluenesulfonic acid → HCID 57585896, compound

Participants

Reaction Steps

1-Acetyl-5-{[4-(1,3-dioxolan-2-yl)phenyl]oxy}-1H-indazole (835 mg, 2.57 mmol) in 25 mL acetone was treated with MP-TsOH (Argonaut, macroporous polymer supported tosic acid, approximately 200 mg, 0.28 mmol) and stirred for 16 hours. The reaction was filtered and concentrated to provide 4-[(1-acetyl-1H-indazol-5-yl)oxy]benzaldehyde quantitatively, which was used without further purification.

Provenance & Evidence