p-Toluenesulfonic acid → HCID 57585869, compound

Participants

Reaction Steps

A mixture of 5-{[4-(1,3-dioxolan-2-yl)phenyl]oxy}-2,7-bis(trifluoromethyl)-1H-benzimidazole (0.260 g, 0.622 mmol) and MP-TSOH (Argonaut, macroporous polymer supported tosic acid, approximately 0.842 g, 1.24 mmol) in acetone (2 mL) was stirred for 3 h, then filtered and concentrated to give the desired 4-{[2,4-bis(trifluoromethyl)-1H-benzimidazol-6-yl]oxy}benzaldehyde which was used without further purification.

Provenance & Evidence