HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → Ethanethioic acid trans-(+/-)-S-[5-[(4-fluorophenoxy)methyl]tetrahydro-3-furanyl]ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethanethioic acid trans(+/-)-S-[tetrahydro-5-[[[(trifluoromethyl)sulfonyl]oxy]methyl]-3-furanyl]ester | HCID 86750748 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Ethanethioic acid trans-(+/-)-S-[5-[(4-fluorophenoxy)methyl]tetrahydro-3-furanyl]ester | HCID 86750320 | 73.7% |
Reaction Steps
The title compound is prepared by the procedure of Example 23 using 1.49 g of product from Example 22 in 1 ml of methylene chloride, 0.542 g of 4-fluorophenol, 2.5 ml of Hunig's base and 3 ml of methylene chloride to give 0.963 g of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623081 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-e1c3bd9240b24596865a0ccb782742f0 |
| Source note | uspto-grants-1997_04 |