HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol hydrochloride → trans-(+/-)-N-[(Tetrahydro-4-mercapto-2-furanyl)methyl]-N-(phenylmethoxy)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol hydrochloride | HCID 21912024 | — |
| Reactant | Sodium methanolate methanol | HCID 23694274 | — |
| Reactant | Ethanethioic acid trans-(+/-)-S-[5-[[Acetyl(phenylmethoxy)amino]methyl]tetrahydro-3-furanyl]ester | HCID 86750754 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | trans-(+/-)-N-[(Tetrahydro-4-mercapto-2-furanyl)methyl]-N-(phenylmethoxy)acetamide | HCID 86750753 | 60.4% |
Reaction Steps
The title compound is prepared by the procedure of Example 16 using 0.390 g of product from Example 72, 0.580 ml of 25% sodium methoxide/methyl alcohol, 0.850 ml of tetrahydrofuran and 1.26 ml of 2N hydrochloric acid/isopropyl alcohol to give 0.205 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623081 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-90eaad4618504011afff5937789a029e |
| Source note | uspto-grants-1997_04 |