HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → (2R-trans)-1-[2-[[[[4-(Acetylthio)tetrahydro-2-furanyl]methoxy]hydoxyphosphinyl]oxy]ethyl]pyridinium hydroxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Ethanethioic acid (3S-trans)-S-[5-[[[(2-bromoethoxy)hydroxyphosphinyl]oxy]methyl]-tetrahydro-3-furanyl]ester | HCID 57157666 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2R-trans)-1-[2-[[[[4-(Acetylthio)tetrahydro-2-furanyl]methoxy]hydoxyphosphinyl]oxy]ethyl]pyridinium hydroxide | HCID 86750755 | — |
Reaction Steps
The title compound is prepared by the procedure of Example 90 using 0.50 g of product from Example 93, 3 ml of pyridine, 4 g of Amberlyst-21, and 10 ml of methyl alcohol to give 0.233 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623081 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-b27a442ae6fd4076b425b9af9201dc0c |
| Source note | uspto-grants-1997_04 |