HCID 67195387, compound → HCID 67197052, compound

Participants

Reaction Steps

A solution of 4-(7-chloro-quinolin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (2.09 g, 5.78 mmol) in dioxane (30 mL) and 4 M HCl in dioxane (20 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 262.3 [M+H]+.

Provenance & Evidence