反应详情

温度

95 °C

A mixture of 9.25 g of product from Example 172, 15 ml of water and 1.5 g of DOWEX-50W-X8 (100-200 mesh, hydrogen form) is heated at 95° C. for 4 hours. The reaction mixture is cooled to room temperature, filtered and the residue washed with water. The filtrate is treated with toluene and concentrated in vacuo to give 1.1 g of the desired product as a sticky yellow oil.

1. temperatureThe reaction mixture is cooled to room temperature
2. filtrationfiltered
3. washthe residue washed with water
4. additionThe filtrate is treated with toluene
5. concentrationconcentrated in vacuo