Aniline → HCID 25205188, compound

HRID 548050Notes

Reaction equation

HRID 548050 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[S:9]([C:12]1[CH:21]=[CH:20][C:15]([C:16]([O:18]C)=[O:17])=[CH:14][CH:13]=1)(=[O:11])=[O:10].Cl[CH2:23][C:24]1[CH:29]=[CH:28][C:27]([O:30][CH3:31])=[CH:26][CH:25]=1>>[CH3:31][O:30][C:27]1[CH:28]=[CH:29][C:24]([CH2:23][N:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[S:9]([C:12]2[CH:21]=[CH:20][C:15]([C:16]([OH:18])=[O:17])=[CH:14][CH:13]=2)(=[O:11])=[O:10])=[CH:25][CH:26]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 699934-Methyloxybenzyl chlorideHCID 4738388Methyl 4-(Chlorosulfonyl)benzoate

Product 1

HCID 25205188HCID 25205188, compound

Procedure

Prepared as in example 5-10 from aniline, methyl 4-(chlorosulfonyl)benzoate (Example 5-10c) and 1-(chloromethyl)-4-methoxybenzene. MS (M−H, 396.1); 1H NMR (400 MHz, DMSO-d6): δ, ppm: 3.66 (s, 3H), 4.73 (s, 2H), 6.78 (d, J=8.4 Hz, 2H), 7.00 (d, J=7.6 Hz, 2H), 7.12 (d, J=8.0 Hz, 2H), 7.24 (d, J=8.0 Hz, 2H), 8.11 (d, J=8.4 Hz, 2H), 13.49 (s, 1H).

Sources & evidence

ORD record
ord-923e315cbaf449f68a4477fa969ed215
Source dataset
uspto-grants-2011_05
Patent number
US07939671B2

Reaction notes

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