Glycine methyl ester → Methyl 2-(2-(methylthio)benzylamino)acetate

HRID 548117Notes

Reaction equation

HRID 548117 reaction equation
[CH3:1][O:2][C:3](=[O:6])[CH2:4][NH2:5].[CH3:7][S:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=O>>[CH3:7][S:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH2:11][NH:5][CH2:4][C:3]([O:2][CH3:1])=[O:6]

Participants

3

Reactant 2

HCID 69221Glycine methyl esterHCID 2864432-(Methylthio)benzaldehyde

Product 1

HCID 57422438Methyl 2-(2-(methylthio)benzylamino)acetateYield 50%

Procedure

Prepared as in example 10-10a from glycine methyl ester and 2-(methylthio)benzaldehyde. Yield 50%. MS M+H calculated 226.1; found 226.1.

Sources & evidence

ORD record
ord-88506b869f3148fea13cec72a8c65117
Source dataset
uspto-grants-2011_05
Patent number
US07939671B2

Reaction notes

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