Dichloromethane → HCID 86624069, compound

Participants

Reaction Steps

tert-Butyl {2-[3-(3,5-dimethylbenzyloxy)-2-phenylpropylcarbamoyl]ethyl}carbamate (1.17 g, 89%) [Compound 111] was produced from the compound produced in Example 24 (0.92 g, 3.0 mmol), 3-N-tert-butyloxycarbonylpropionic acid (0.68 g, 3.6 mmol), triethylamine (0.42 mL, 3.0 mmol), WSC.HCl (0.69 g, 3.6 mmol) and CH2Cl2 (10 mL) in the same manner as Example 29. In the same manner as Example 95, Compound 112 (0.94 g, 100%) was produced from Compound III (1.10 g, 2.5 mmol), 4 mol/L hydrogen chloride/dioxane (4.5 mL) and dioxane (4.5 mL).

Provenance & Evidence