HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 2,5-Anhydro-6-azido-1,3,6-trideoxy-D-ribo-hexitol 4-Methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2,5-Anhydro-6-azido-1,3,6-trideoxy-D-ribo-hexitol | HCID 86750354 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 2,5-Anhydro-6-azido-1,3,6-trideoxy-D-ribo-hexitol 4-Methanesulfonate | HCID 86750356 | 48.7% |
Reaction Steps
The title compound is prepared by the procedure of Example 277 using 0.192 g of product from Example 338, 0.316 g of Hunig's base, 0.280 g of methanesulfonyl chloride and 0.35 ml of methylene chloride to give after chromatography (Silica gel: 30% ethyl acetate/hexane) 0.140 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623081 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-62323ef1a777454e91fb92b70e40184f |
| Source note | uspto-grants-1997_04 |